Our understanding of neurogenetic disorders have increased dramatically in the last 20 years due to recent advancements in genetic methodologies. The promise of personalized medicine and the power of human genome sequencing have changed how scientists approach the field of neuroscience. This course covers classical genetics, non-Mendelian inheritance, and epigenetics as they relate to neurodevelopmental and neurological disorders. Practical applications including genome-wide association (GWAS), next-generation sequencing, epigenetics, genome editing and screening methods will also be discussed.
Learning forms the foundation of social interactions in human and non-humans: the ability to learn and memorize locations, situations, individuals, facts and tasks forms are fundamental. We will discuss the cellular and molecular mechanism underlying learning and memory and the most highly studied model systems. Approaches to these processes along with human diseases presenting with learning and memory deficits will be discussed.